Name | rosarin |
Synonyms | rosarin ROSARIN (2E)-3-phenyl-2-propenyl6-O-.alpha.-L-arabinofuranosyl-(9CI) [(E)-3-Phenyl-2-propenyl]6-O-α-L-arabinofuranosyl-β-D-glucopyranoside [(E)-3-Phenyl-2-propenyl]6-O-(α-L-arabinofuranosyl)-β-D-glucopyranoside b-D-Glucopyranoside,(2E)-3-phenyl-2-propen-1-yl 6-O-a-L-arabinofuranosyl- β-D-Glucopyranoside, (2E)-3-phenyl-2-propen-1-yl 6-O-α-L-arabinofuranosyl- (2E)-3-Phenylprop-2-en-1-yl 6-O-alpha-L-arabinofuranosyl-beta-D-glucopyranoside beta-D-glucopyranoside, (2E)-3-phenyl-2-propen-1-yl 6-O-alpha-L-arabinofuranosyl- |
CAS | 84954-93-8 |
InChI | InChI=1/C20H28O10/c21-9-12-14(22)17(25)20(29-12)28-10-13-15(23)16(24)18(26)19(30-13)27-8-4-7-11-5-2-1-3-6-11/h1-7,12-26H,8-10H2/b7-4+/t12-,13+,14-,15+,16-,17+,18+,19+,20+/m0/s1 |
Molecular Formula | C20H28O10 |
Molar Mass | 428.43 |
Density | 1.48±0.1 g/cm3(Predicted) |
Boling Point | 730.8±60.0 °C(Predicted) |
Specific Rotation(α) | (c, 5 in CHCl3/MeOH 1:1)-76.1 |
Flash Point | 395.8°C |
Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
Vapor Presure | 2.03E-22mmHg at 25°C |
Appearance | White-like powder |
pKa | 12.89±0.70(Predicted) |
Storage Condition | 2-8℃ |
Refractive Index | 1.634 |
MDL | MFCD04039808 |
Physical and Chemical Properties | White-like powder, soluble in methanol, ethanol, DMSO and other organic solvents, from Rhodiola rosea. |
In vitro study | Rosarin (0-50 μg/ml; 18 hours) pretreats 30 mins in LPS-induced BV-2 cells supresses iNOS and cytokines expression in a concentration-dependent manner in the murine BV2 cells. |
HS Code | 29389090 |
biological activity | Rosarin is a cinnamyl alcohol glycoside isolated from Rhodiola rosea. Rosarin has anti-inflammatory and neuroprotective effects. Rosarin inhibits the expression of pro-inflammatory factors iNOS,IL-1β and TNF-α in mouse kidney and brain prefrontal cortex. |
in vitro study | Rosarin (0-50μg/ml; 18 hours) preparations 30 mins in LPS-induced BV-2 cells supresses iNOS and cytokines expression in a concentration-dependent manner in the murine BV2 cells. |
Chemical properties | white powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Rhodiola rosea. |
uses | Luo Serin has the effects of anti-fatigue, anti-cancer, anti-oxidation and enhancing immunity. for content determination/identification/pharmacological experiments. |